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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

Ngai 2000.

Methods Randomisation schedule as described by Meinert. Sealed envelopes with serial numbers were prepared. At enrolment, a serial number was given according to the sequence of entry.
Participants 139 pregnant women (group I: 70, group II: 69)
Inclusion criteria: healthy women between 16‐35 years, 14‐20 weeks gestation.
Exclusion criteria: regular use of prescription drugs, IUD in utero, nursing mothers, multiple pregnancies, heavy smokers.
Interventions All: 200mg mifepristone + (36 ‐ 48 h later):
Group I: 400 μg misoprostol oral and a vaginal placebo (vitamin B6) every 3 hours;
Group II: 200 μg misoprostol vaginally and an oral placebo (vitamin B6) every 3 hours.
Outcomes Primary outcome: abortion within 24 hours.
Secondary outcomes: induction to abortion interval, side‐effects.
Notes Definition of abortion: not specified.
If the placenta was incomplete, an evacuation of the uterus was carried out under general anaesthesia.
No major complications occurred.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ adequate
Blinding? 
 All outcomes Low risk Blinding for participants.
Free of other bias? Unclear risk No statistically significant differences between the groups in terms of maternal age and gestational age.