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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

Nielsen 1975.

Methods Randomisation.
Participants 32 pregnant women (group I: 16, group II: 16)
Inclusion criteria: gestation more than 14 weeks.
Exclusion criteria: none reported.
Interventions Group I: suprapublical/transvaginal injection of 20% saline, preceded by removal of 50 mL of amniotic fluid. Amount of saline depending on gestation; 14th week 75 mL, 15th week 100 mL, >16th week 150 mL.
Group II: suprapublical/transvaginal injection of 40 mg of PGF, preceded by removal of 50 mL of amniotic fluid.
Both groups received an 10 IU/h oxytocin drip (100IU in one litre of 5% glucose) within half an hour. If abortion did not occur before 200IU oxytocin was given, the infusion was stopped for 6‐8h and then restarted. PG/saline injection was not repeated.
Outcomes Abortion interval, complications, side‐effects.
Notes Definition of abortion: none given.
Curettage was performed in cases which were considered incomplete.
No major complications described.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk B ‐ unclear
Blinding? 
 All outcomes High risk  
Free of other bias? Low risk No apparant differences between the groups in terms of maternal age, gestational age and parity.