Olund 1978.
Methods | Randomly assigned. | |
Participants | 92 pregnant women (group I: 23, group II: 23, group III: 23, group IV: 23) Inclusion criteria: 13‐25 weeks gestation. Exclusion criteria: none described. |
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Interventions | Group I: extra‐amniotic instillation of 0.1% solution of rivanol, 10 ml per gestational week. Maximum of 150 ml. Group II: extra‐amniotic instillation of 1 ml of saline containing 0.25 mg PGF2α per ml, 3 ml every 2 hours for up to 24 hours. At a gestational age >16 weeks, the dose was doubled. Group III: Rivanol + PGF2α, as in group I and II. Group IV: Rivanol + a half dose of PGF2α, as in group III, except for a half dose of PGF2α. NB: For our analysis, we included group I and II. |
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Outcomes | Abortion time, abortion interval, side‐effects. | |
Notes | No definition of abortion was given. No major complications described. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Low risk | B ‐ unclear |
Blinding? All outcomes | High risk | |
Free of other bias? | Low risk | No statistically significant differences between the groups in terms of maternal age, gestational age and parity. |