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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

Olund 1978.

Methods Randomly assigned.
Participants 92 pregnant women (group I: 23, group II: 23, group III: 23, group IV: 23)
Inclusion criteria: 13‐25 weeks gestation.
Exclusion criteria: none described.
Interventions Group I: extra‐amniotic instillation of 0.1% solution of rivanol, 10 ml per gestational week. Maximum of 150 ml.
Group II: extra‐amniotic instillation of 1 ml of saline containing 0.25 mg PGF per ml, 3 ml every 2 hours for up to 24 hours. At a gestational age >16 weeks, the dose was doubled.
Group III: Rivanol + PGF, as in group I and II.
Group IV: Rivanol + a half dose of PGF, as in group III, except for a half dose of PGF.
NB: For our analysis, we included group I and II.
Outcomes Abortion time, abortion interval, side‐effects.
Notes No definition of abortion was given.
No major complications described.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk B ‐ unclear
Blinding? 
 All outcomes High risk  
Free of other bias? Low risk No statistically significant differences between the groups in terms of maternal age, gestational age and parity.