Sorensen 1984.
Methods | Use of random numbers. | |
Participants | 39 pregnant women (group I: 20, group II: 19) Inclusion criteria:13‐24 weeks of gestation. Exclusion criteria: intra‐uterine fetal death, cardiopulmonary disease, nephropathy, liver diseases, previous operation on the uterus |
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Interventions | Group I: 2x PGE2 0.75 mg within 5 hours intracervical/extra amniotic, 5 hours, later followed by oxytocin infusion 0.15 IU/min if no contractions. Group II: PGF2α 40 mg intra‐amniotically 5 hours later followed by oxytocin drip 0.15 IU/min if no contractions. |
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Outcomes | Primary outcomes: abortion success rate, induction‐abortion interval. Secondary outcomes: side‐effects. |
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Notes | Definition of abortion: expulsion of fetus. If the placenta was not expelled within 2 hours, an evacuation of the uterus was performed. No major complications reported. |
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Risk of bias | ||
Bias | Authors' judgement | Support for judgement |
Allocation concealment? | Low risk | B ‐ unclear |
Blinding? All outcomes | High risk | |
Free of other bias? | Low risk | No statistically significant differences between the groups in terms of maternal age, gestational age and parity. |