Steyn 1993.

Methods	Randomisation using the balanced block method. Instructions were placed in sealed envelopes.
Participants	20 pregnant women (group I: 10, group II: 10) Inclusion criteria: 14‐26 weeks of gestation. Exclusion criteria: fetal death on admission, previous uterine scars, history of asthma, active vaginal or intra‐uterine infection, anhydramnios.
Interventions	Group I: 1.5 mg prostaglandin E2 (PGE2) gel extra‐amniotically. Group II: 25 mg prostaglandin F2α (PGF2α) intra‐amniotically. Patients in both groups received oxytocin to a maximum dosage of 120 mU per minute if they had not aborted 18 hours after the original administration of either prostaglandin regimen. If the patient had not aborted within 36h, the method was regarded unsuccessful and the managing physician was free to change the management of choice.
Outcomes	Primary outcome: induction to abortion interval. Secondary outcomes: complications, side effects. Proportion of successful inductions and complications.
Notes	Definition of abortion: none given. No information was provided regarding the policy of evacuation of the uterus. No major complications reported.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	A ‐ adequate
Blinding? All outcomes	High risk
Free of other bias?	Low risk	No statistically significant differences between the groups in terms of maternal age, gestational age and parity.