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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

Su 2005.

Methods Random allocation; computer‐generated schedule randomisation; numbered, sealed, opaque envelope; envelopes were drawn in consecutive order.
Participants 125 pregnant women (group I: 61, group II: 64)
Inclusion criteria: 12‐24 weeks gestation.
Exclusion criteria: multiple pregnancies, ≥ 2 previous cesarean sections, missed abortion, oligohydramnios, severe asthma, allergy to prostaglandins.
Interventions Group I: vaginal misoprostol 400 μg /3h, max 5d in 24 hrs.
Group II: intra amniotic PGF2α 1,5mg, max 5d in 24 hrs.
Outcomes Primary outcome: induction to abortion interval.
Secondary outcomes: abortion within 24 and 48 hours, the need for repeat course of medications, evacuation of uterus, adverse effects.
Notes Definition of abortion: expulsion of the fetus.
Evacuation of the uterus was not performed routinely.
No major complications reported.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ adequate
Blinding? 
 All outcomes High risk  
Free of other bias? Low risk No statistically significant differences between the groups in terms of maternal age, gestational age and parity.