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. 2011 Jan 19;2011(1):CD005216. doi: 10.1002/14651858.CD005216.pub2

Thong 1996.

Methods Sealed, opaque envelopes containing either of the two treatment groups. These envelopes were shuffled and numbered consecutively.
Participants 100 pregnant women (group I: 50, group II: 50)
Inclusion criteria: 12‐19 weeks gestation.
Exclusion criteria: <16 years.
Interventions All: 200mg mifepristone, 36 hours later:
Group I: 1mg pessary gemeprost vaginally in 6 hour intervals, max 4 doses in 24 hour. After 24 hours without abortion 1 mg gemeprost in 3 hour intervals, max 24 hours;
Group II: 0.5mg pessary gemeprost vaginally in 6 hour intervals, max 4 doses in 24 h. After 24 hours 1 mg gemeprost in 3 hour intervals.
Outcomes Primary outcome: abortion within 24h.
Secondary outcomes: side‐effects.
Notes Definition of abortion: expulsion of fetus and placenta.
Evacuation of the uterus was carried out if the placenta was not expelled spontaneously or if it was judged to be incomplete.
One woman in group II required a blood transfusion of two units because of heavy bleeding in association with a retained placenta after expulsion of the fetus.
Risk of bias
Bias Authors' judgement Support for judgement
Allocation concealment? Low risk A ‐ adequate
Blinding? 
 All outcomes High risk  
Free of other bias? Low risk No apparent differences between the groups in terms of maternal age, gestational age and parity.