Waldron 1990.

Methods	Randomisation.
Participants	58 pregnant women (group I: 29, group II: 29) Inclusion criteria: 14‐20 weeks of gestation. Exclusion criteria: signs or symptoms of spontaneous abortion, known or suspected hypersensitivity to prostaglandins, cardio‐pulmonary disease, hypertension, urticaria, eczema, ulcerative colitis, diabetes, epilepsy, renal disease, liver disease.
Interventions	Group I: 1 mg gemeprost in vaginal pessaries, 3h interval, maximum of 5 doses. Group II: 20 mg of PGF2α in 40 ml of 20% NaCl, intra‐amniotic. If abortion had not occurred within 24 hours, an alternative treatment was commenced at the discretion of the clinician. Following delivery of the fetus, oxytocin or ergometrine in routine dosages were used at the clinician's discretion, and surgical evacuation of the uterus was performed if the placenta was not delivered within two hours.
Outcomes	Abortion interval, side‐effects, complications.
Notes	Definition of abortion: abortion within 24 hours. If the placenta was not expelled within 2 hours, an evacuation of the uterus was performed. No major complications described.
Risk of bias
Bias	Authors' judgement	Support for judgement
Allocation concealment?	Low risk	B ‐ unclear
Blinding? All outcomes	High risk
Free of other bias?	Low risk	No apparent differences between the groups in terms of maternal age, gestational age and parity.