Table 2.
Associations of C3 with the presence of MAFLD by univariate regression analyses
| Characteristics | OR (95% CI) | P value |
| Age | 1.019 (1.012 to 1.026) | <0.001 |
| WC | 1.167 (1.154 to 1.181) | <0.001 |
| BMI | 1.570 (1.518 to 1.624) | <0.001 |
| SBP | 1.033 (1.028 to 1.037) | <0.001 |
| DBP | 1.054 (1.047 to 1.061) | <0.001 |
| ALT | 1.048 (1.042 to 1.054) | <0.001 |
| AST | 1.046 (1.037 to 1.056) | <0.001 |
| GGT | 1.012 (1.010 to 1.014) | <0.001 |
| TB | 1.024 (1.012 to 1.037) | <0.001 |
| TG | 1.971 (1.827 to 2.127) | <0.001 |
| TC | 1.352 (1.253 to 1.459) | <0.001 |
| HDL-C | 0.074 (0.057 to 0.097) | <0.001 |
| LDL-C | 1.310 (1.196 to 1.434) | <0.001 |
| Cr | 1.015 (1.011 to 1.020) | <0.001 |
| UA | 1.008 (1.008 to 1.009) | <0.001 |
| Glu | 1.678 (1.552 to 1.814) | <0.001 |
| HbA1c | 1.977 (1.772 to 2.206) | <0.001 |
| hsCRP | 1.015 (1.002 to 1.027) | 0.019 |
| INS | 1.223 (1.201 to 1.246) | <0.001 |
| HOMA-IR | 2.267 (2.107 to 2.440) | <0.001 |
| C3 | 1.045 (1.040 to 1.049) | <0.001 |
| Smoke | 1.287 (1.102 to 1.504) | 0.001 |
| Drinking | 1.499 (1.270 to 1.769) | <0.001 |
| Female | 0.433 (0.373 to 0.503) | <0.001 |
| Physical exercise | 0.717 (0.617 to 0.832) | <0.001 |
| BMI >23 | 12.248 (9.679 to 15.498) | <0.001 |
| Diabetes | 3.459 (2.742 to 4.365) | <0.001 |
ALT, alanine aminotransferase; AST, aspartate aminotransferase; BMI, body mass index; C3, complement C3; Cr, creatinine; DBP, diastolic blood pressure; GGT, γ-glutamyl transpeptidase; Glu, glucose; HbA1c, glycosylated haemoglobin A1c; HDL-C, high-density lipoprotein cholesterol; HOMA-IR, homoeostasis model assessment of insulin resistance; hsCRP, High sensitivity C reactive protein; INS, insulin; LDL-C, low-density lipoprotein cholesterol; MAFLD, metabolic-associated fatty liver disease; SBP, systolic blood pressure; TB, total bilirubin; TC, total cholesterol; TG, triglyceride; UA, uric acid; WC, waist circumference.