Table 3.

Adverse events

Event	Grade 1	Grade 2	Grade 3	Grade 4	Unknown	Total	Grade ≥3
Nausea	7 (38.9)	4 (22.2)	1 (5.6)	–	–	12 (66.7)	1 (5.6)
Appetite loss	2 (11.1)	4 (22.2)	5 (27.8)	–	–	11 (61.1)	5 (27.8)
Hiccup	4 (22.2)	7 (38.9)	–	–	–	11 (61.1)	–
Constipation	4 (22.2)	5 (27.8)	–	–	–	9 (50.0)	–
Rush	3 (16.7)	4 (22.2)	–	–	–	7 (38.9)	–
Anemia	–	4 (22.2)	3 (16.7)	–	–	7 (38.9)	3 (16.7)
Fatigue	2 (11.1)	4 (22.2)	–	–	–	6 (33.3)	–
Nasopharyngitis	3 (16.7)	2 (11.1)	–	–	–	5 (27.8)	–
Insomnia	4 (22.2)	1 (5.6)				5 (27.8)	–
Neutropenia	–	5 (27.8)	–	–	–	5 (27.8)	–
Diarrhea	1 (5.6)	3 (16.7)	–	–	–	4 (22.2)	–
Fever	4 (22.2)	–	–	–	–	4 (22.2)	–
Peripheral neuropathy	2 (11.1)	1 (5.6)	1 (5.6)		–	4 (22.2)	1 (5.6)
Leukopenia	–	3 (16.7)	1 (5.6)	–	–	4 (22.2)	1 (5.6)
Mucositis	–	3 (16.7)	–	–	–	3 (16.7)	–
Pneumonia	–	2 (11.1)	1 (5.6)	–	–	3 (16.7)	1 (5.6)
Dysgeusia	1 (5.6)	1 (5.6)	–	–	1 (5.6)	3 (16.7)	–
Hearing impairment	2 (11.1)	1 (5.6)	–	–	–	3 (16.7)	–
Abdominal discomfort	1 (5.6)	1 (5.6)	–	–	–	2 (11.1)	–
Angular cheilitis	1 (5.6)	1 (5.6)	–	–	–	2 (11.1)	–
Hyponatremia	–	–	1 (5.6)	1 (5.6)	–	2 (11.1)	2 (11.1)
Muscle pain	1 (5.6)	1 (5.6)	–	–	–	2 (11.1)	–
Back pain	–	1 (5.6)	1 (5.6)	–	–	2 (11.1)	1 (5.6)

Values are n (%).