Table 1.
Demographics and characteristics of patients admitted with non-ST-segment elevation myocardial infarction, stratified by shock index
| Characteristic | Shock index < 0.7 (N = 12 548) | Shock index ≥ 0.7 (N = 5753) | P-value |
|---|---|---|---|
| Demographics | |||
| Age | 63 ± 0.2 | 65 ± 0.2 | 0.0006 |
| Female | 4846 (39%) | 2624 (46%) | <0.0001 |
| White | 7499 (60%) | 3595 (62%) | 0.1 |
| Medical history | |||
| Smoker | 3951 (31%) | 1723 (30%) | 0.9 |
| Diabetes mellitus | 5261 (42%) | 2463 (43%) | 0.6 |
| Chronic kidney disease | 3200 (32%) | 1946 (40%) | <0.0001 |
| Prior coronary revascularization | 4317 (34%) | 1655 (29%) | 0.0007 |
| In-hospital clinical course | |||
| Acute pulmonary oedema/heart failure | 3712 (30%) | 2408 (42%) | <0.0001 |
| Ventricular fibrillation/arrest/asystole | 558 (4%) | 634 (11%) | <0.0001 |
| Cardiogenic shock | 200 (2%) | 311 (5%) | <0.0001 |
| Risk scores | |||
| Killip class | 1.6 ± 0.01 | 2.0 ± 0.02 | <0.0001 |
| Elevated Killip class (≥3) | 3775 (30%) | 2503 (44%) | <0.0001 |
| TIMI score | 4.3 ± 0.01 | 4.2 ± 0.02 | 0.0003 |
| Elevated TIMI score (≥5) | 5058 (40%) | 2111 (37%) | 0.04 |
| GRACE scorea | 118 ± 0.9 | 142 ± 1.3 | <0.0001 |
| Elevated GRACE score (>140) | 2914 (29%) | 2449 (50%) | <0.0001 |
| Hospital procedures | |||
| Cardiopulmonary resuscitation/cardioversion | 409 (3%) | 495 (9%) | <0.0001 |
| Angiography | 7304 (58%) | 2052 (36%) | <0.0001 |
| Coronary revascularization | 5162 (41%) | 1069 (19%) | <0.0001 |
| Hospital medications | |||
| Aspirin | 11253 (90%) | 4810 (84%) | <0.0001 |
| Antiplatelets | 7349 (59%) | 1978 (34%) | <0.0001 |
| Beta blockers | 11181 (89%) | 4662 (81%) | <0.0001 |
| Statins/lipid-lowering agents | 9588 (76%) | 3495 (61%) | <0.0001 |
| ACEi/ARB | 8123 (65%) | 3225 (56%) | <0.0001 |
The community surveillance component of the Atherosclerosis Risk in Communities Study, 2000–2014.
Values are presented as mean ± standard error or number (percentage).
ACEi/ARB, angiotensin-converting enzyme inhibitor/angiotensin receptor blocker; GRACE, Global Registry of Acute Coronary Syndrome; TIMI, thrombolysis in myocardial ischaemia.
a
Chronic kidney disease and GRACE score limited to hospitalizations from 2004 to 2014 with available serum creatinine abstractions (N = 14 911; 3390 missing).