Table 2.

Practical application of the SPUM-ACS Score

SPUM-ACS SCORE		# 1: 79 yo NSTEMI	# 2: 69 yo Critical STEMI	# 3: 63 yo Benign STEMI
Risk	0.04938 * (age - 63.47)	0.7669 (79)	0.2731 (69)	-0.02321 (63)
	0.2569 * (gluc - 6.287)	-0.0994 (5.9)	1.8273 (13.4)	-0.1508 (5.7)
	0.0002569 * (NT-proBNP - 389.3)	3.167 (11264)	0.7329 (2906)	-0.01552 (336)
	-0.044 * (LVEF - 50.87)	-0.1817 (55)	0.6983 (35)	-0.402 (60)
	0.971 * (Killip - 1)	0 (1)	0 (1)	0 (1)
	2.297 * h/o PAD	0 (no)	0 (no)	0 (no)
	2.108 * h/o malignancy	0 (no)	0 (no)	0 (no)
	1.354 * CPR	0 (no)	1.354 (yes)	0 (no)
Sum		3.653	4.886	-0.592
Final Score [0,100]	100/(1+exp(-sum + 0.55))	96	99	24

Calculation coefficients for each variable in the SPUM-ACS Score are displayed. A score calculator is freely available as supplement online material (Supplemental File “SPUM-ACS Score.html”). For illustrative purposes, the SPUM-ACS Score was computed for three cohort patients, each representing a typical ACS scenario:

Example #1) Haemodynamically stable 79-year-old patient with NSTEMI and presenting on admission NT-proBNP level of 11264 ng/L, plasma glucose of 5.9 mmol/L;

Example #2) 69-year-old patient diagnosed with STEMI, presenting on admission elevated NT-proBNP level (2906 ng/L) and plasma glucose (13.4 mmol/L), with cardiac arrest;

Example #3) 63-year-old patient diagnosed with STEMI, presenting on admission slightly increased NT-proBNP level (336 ng/L) and plasma glucose of 5.7 mmol/L).

Final SPUM-ACS scores are displayed at the bottom.

In case of a missing variable, the corresponding row is to be excluded from the overall sum, i.e., a row holds a value 0 if the respective variable is missing.