Table 1.
Tumor-associated and tumor-specific antigens
| Marker | Full name | Tissue | Malignancy | Ref |
|---|---|---|---|---|
| AFP | Alfa fetoprotein | Fetal liver | Liver, gut, ovaries | [4] |
| CEA | Carcinoembryonic antigen | Blood | Gastric, lung | [4] |
| HSP | Heat shock proteins | Stressed cells | lung, gut, prostate | [4] |
| CA | Carbohydrate antigens | All cells | Gastric, lung, pancreas | [4] |
| MUC1 | Mucin 1 | Epithelial cells | Lung, breast, pancreas | [4] |
| PSA | Prostate-specific antigen | Prostate | Prostate | [4] |
| MAGE | Melanoma-associated antigen | Testis | Lung | [4, 5] |
| NY-ESO-1 | Cancer/testis antigen | Testis | Esophagus | [6–8] |
| SSX-2 | Cancer/testis antigen | Testis | Various cancer | [7, 9, 10] |
| GPC3 | Glypican-3 | Fetal and adult | Liver, lung, melanoma | [4] |
| Midkine | Growth-promoting factor 2 | All cells | Nervous system | [7, 11] |
| EpCAM | Cell adhesion molecule | Epithelial cells | Epithelial carcinomas | [7] |
| PRAME | Preferentially in melanoma | Testis | Lung | [5, 7, 8] |
| WT1 | Wilm’s tumor protein1 | Urinogenital | Kidney | [7, 8] |
| Survivin | Inhibitor of apoptosis | All cells | Bladder | [7, 8, 12] |