Table 3.
Delivery of DRUG by MSC-EXOs
| Aim | Exosomes origin | Loading methods | Administration route | Model | DRUG | References |
|---|---|---|---|---|---|---|
| Breast cancers | HucMSC | Incubation | Intravenous injection | Mice | Paclitaxel | [115] |
| Breast cancers | MSC | Electroporation | In vitro cell experiment | Doxorubicin | [114] | |
| Hepatocellular carcinoma | BMSC | Electroporation | Intravenous injection | Mice | Norcantharidin (NCTD) | [117] |
| Osteosarcoma | BMSC | Dialyze | In vitro cell experiment | Doxorubicin | [119] | |
| Pancreatic cancer | BMSC | Electroporation | Intravenous injection | Mice | Gemcitabine monophosphate(GEMP) | [120] |
| Oral squamous cell carcinoma | MSC | Incubation | Injected subcutaneously | Mice | Cabazitaxel (CTX) | [116] |
| Several cancer cell lines | MSC | Sonication | In vitro cell experiment | Honokiol | [118] |