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. 2021 Oct 30;14:181. doi: 10.1186/s13045-021-01198-9

Fig. 5.

Fig. 5

Potential targeted therapeutic strategies fo r TAMs. a Directly blocking macrophage chemokines or inhibiting their receptors. b Using clodronate to deplete macrophages. c Increasing the quantity of M1 or promoting the M2-to-M1 conversion to lift the ratio of M1/M2. d Blocking TAMs secretions acting on cancer cells. e CAR macrophage therapy. f TAMs-based immune vaccine s. g TAMs nanobiotechnology