TABLE 2.
Univariate Predictors of LT Listing or Liver-Related Death After PSC Diagnosis
| Predictor | HR | P Value |
|---|---|---|
| Age at diagnosis (per 1.0 year) | 1.03 | 0.161 |
| Male sex (vs. female) | 0.83 | 0.373 |
| Presence of IBD (vs. no IBD) | 1.01 | 0.311 |
| Ulcerative colitis phenotype (vs. no IBD) | 0.93 | 0.720 |
| Crohn’s disease phenotype (vs. no IBD) | 0.92 | 0.752 |
| Features of overlap with AIH (vs. absence) | 0.68 | 0.096 |
| Large-duct phenotype (vs. small duct) | 1.76 | 0.038 |
| Hemoglobin (per 1.0-mg/dL increase) | 0.89 | 0.036 |
| Platelet count (per 100,000/μL increase) | 0.62 | <0.001 |
| INR (per 1.0 increase) | 1.07 | 0.572 |
| Total protein (per 1.0-g/dL increase) | 0.71 | 0.008 |
| Albumin (per 1.0-g/dL increase) | 0.37 | <0.001 |
| GGT (per 100 U/L) | 1.10 | <0.001 |
| ALP (per 1.0 × ULN for age) | 1.16 | 0.001 |
| AST (per 100 U/L) | 1.02 | 0.460 |
| ALT (per 100 U/L) | 0.99 | 0.549 |
| Total bilirubin (per 1.0-mg/dL increase) | 1.16 | <0.001 |
| Sodium (per 1-meq/L increase) | 1.07 | 0.062 |
| Creatinine (per 1.0-mg/dL increase) | 0.41 | 0.123 |
Abbreviation: ULN, upper limit of normal.