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. Author manuscript; available in PMC: 2022 Mar 1.
Published in final edited form as: Hepatology. 2020 Dec 19;73(3):1074–1087. doi: 10.1002/hep.31393

TABLE 2.

Univariate Predictors of LT Listing or Liver-Related Death After PSC Diagnosis

Predictor HR P Value
Age at diagnosis (per 1.0 year) 1.03 0.161
Male sex (vs. female) 0.83 0.373
Presence of IBD (vs. no IBD) 1.01 0.311
Ulcerative colitis phenotype (vs. no IBD) 0.93 0.720
Crohn’s disease phenotype (vs. no IBD) 0.92 0.752
Features of overlap with AIH (vs. absence) 0.68 0.096
Large-duct phenotype (vs. small duct) 1.76 0.038
Hemoglobin (per 1.0-mg/dL increase) 0.89 0.036
Platelet count (per 100,000/μL increase) 0.62 <0.001
INR (per 1.0 increase) 1.07 0.572
Total protein (per 1.0-g/dL increase) 0.71 0.008
Albumin (per 1.0-g/dL increase) 0.37 <0.001
GGT (per 100 U/L) 1.10 <0.001
ALP (per 1.0 × ULN for age) 1.16 0.001
AST (per 100 U/L) 1.02 0.460
ALT (per 100 U/L) 0.99 0.549
Total bilirubin (per 1.0-mg/dL increase) 1.16 <0.001
Sodium (per 1-meq/L increase) 1.07 0.062
Creatinine (per 1.0-mg/dL increase) 0.41 0.123

Abbreviation: ULN, upper limit of normal.