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Correlations between age and anti-HCoV (HKU1 S1-RBD, NL63 S1-RBD, OC43 S1, and 229E S1-RBD) IgG antibody titers in prepandemic samples from children and adults undergoing adeotonsillectomy. The regression lines and P values are shown for children (red) and adults (blue). Abbreviations: HCoV, human coronavirus; IgG, immunoglobulin G; NS, not significant; RBD, receptor-binding domain; S, spike.
