TABLE 1.

Genotypes and MICs of tigecycline against parental strains and their resistant subpopulations in the absence or presence of efflux pump inhibitors

Population-level resistance, isolate	Specimen type	STa	TIG MIC (mg/liter)b
			P	RP	RP + CCCP	RP + PAβN
Heteroresistant
FA56	Sputum	191	2	16	4	8
FA83	Sputum	191	2	16	0.5	8
FA154	Sputum	191	2	16	0.5	8
FA1318	Sputum	357	2	16	4	8
FA1323	Sputum	357	2	16	2	8
F-1757	Blood	357	2	16	2	8
F-2420	Blood	357	2	16	1	8
FA72	Sputum	191	4	32	2	8
Homogeneous
FA1398	Sputum		2
FA1331	Sputum		4
FA87	Sputum		64
ATCC 19606			1

^aST, sequence type.

^bTIG, tigecycline; P, parental strain; RP, resistant population.