TABLE 2.
Phenotypic and genotypic characteristics of K. pneumoniae strain HK31 and its transconjugants
| Strain | Species | MIC (μg/ml) for:a |
|||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZI | CTX | CAZ | CIP | CHL | ATM | AMP | AMK | GEN | MEM | CLS | TGC | erm(B)b | Conjugation efficiency | ||
| HK31 | K. pneumoniae | 128 | >128 | >128 | 128 | 64 | >128 | >128 | >128 | >128 | <0.25 | 32 | 0.5 | + | NA |
| J53 | E. coli | 2 | <0.25 | 0.5 | <0.25 | 2 | <0.25 | 8 | 2 | 2 | <0.25 | <0.25 | <0.25 | − | NA |
| J53TC | E. coli | 64 | >128 | 2 | <0.25 | 2 | 64 | >128 | 2 | 2 | <0.25 | <0.25 | <0.25 | + | 1.33E−06 |
| PY1 | S. Typhimurium | 4 | <0.25 | 8 | <0.25 | 4 | <0.25 | 8 | 2 | 2 | <0.25 | 1 | 0.5 | − | NA |
| PY1TC | S. Typhimurium | 64 | >128 | 32 | <0.25 | 4 | 128 | >128 | 2 | 2 | <0.25 | 1 | 0.5 | + | 3.5E−07 |
| 25922 | E. coli | 2 | <0.25 | 0.5 | <0.25 | 4 | <0.25 | 8 | 2 | 4 | <0.25 | 0.5 | 0.5 | NA | NA |
All tests were performed in duplicate, and each test included three biological replicates. AZI, azithromycin; CTX, cefotaxime; CAZ, ceftazidime; CIP, ciprofloxacin; CHL, chloramphenicol; ATM, aztreonam; AMP, ampicillin; AMK, amikacin; GEN, gentamicin; MEM, meropenem; CLS, colistin; TGC, tigecycline.
NA, not available.