TABLE 4.

Factors associated with Abbott SARS-CoV-2 seronegativity, among participants with previous PCR-confirmed SARS-CoV-2 infection^a

Parameter	All participants (n)	Negative result (n)	Negative %	Unadjusted			Adjusted
				OR	95% CI	P valueb	OR	95% CI	P valueb
Total	274	124	45.3
Age group (in yrs)
18–29	79	41	51.9	*c			*
30–39	79	43	54.4	1.11	0.59–2.07	0.750	0.99	0.46–2.15	0.982
40–49	59	17	28.8	0.38	0.18–0.76	0.007	0.36	0.15–0.82	0.017
50–59	45	19	42.2	0.68	0.32–1.41	0.301	0.70	0.28–1.71	0.429
60+	12	4	33.3	0.46	0.12–1.60	0.238	0.25	0.05–1.04	0.065
Sex
Female	201	102	50.7	*			*
Male	73	22	30.1	0.42	0.25–0.74	0.003	0.30	0.15–0.60	<0.001
Ethnicity
Irish (white)	173	94	54.3	*			*
Any other white background	35	12	34.3	0.44	0.20–0.92	0.033	0.49	0.2–1.19	0.118
Any Asian background	56	14	25.0	0.28	0.14–0.54	<0.001	0.28	0.12–0.60	0.001
Any African/black background	7	2	28.6	0.34	0.04–1.61	0.200	0.47	0.05–3.33	0.449
Other	3	2	66.7	1.68	0.15–36.6	0.067	2.33	0.14–70.6	0.566
Close contact with a case of COVID-19d
Yes	155	65	41.9	0.71	0.44–1.15	0.178	0.63	0.34–1.16	0.137
No	117	59	50.4	*			*
Main type of patient contacte
No patient contact	46	24	52.2	*			*
Daily contact non-COVID-19 patients	162	74	45.7	0.77	0.39–1.49	0.437	0.79	0.34–1.80	0.577
Daily contact known or suspected COVID-19 patients	66	26	39.4	0.60	0.27–1.27	0.182	0.83	0.32–2.14	0.694
Severity of symptomsd
No symptoms	6	3	50.0	0.82	0.15–4.61	0.816	0.86	0.12–6.29	0.876
Minor symptoms	113	62	54.9	*			*
Significant symptoms	130	55	42.3	0.60	0.36–1.00	0.051	0.50	0.27–0.92	0.028
Severe symptoms (hospitalized)	23	4	17.4	0.17	0.04–0.49	0.003	0.19	0.05–0.61	0.008
HCW role
Administration	18	9	50.0	*			Not included in the model
Allied health care	34	19	55.9	1.27	0.40–4.03	0.686
General support	10	5	50.0	1.00	0.21–4.81	1.00
Health care assistant	24	5	20.8	0.26	0.06–0.98	0.053
Medical/dental	62	29	46.8	0.88	0.30–2.54	0.809
Nursing/midwifery	124	55	44.4	0.80	0.29–2.17	0.653
Other	2	2	100.0	NAf	NA	NA
No. of mo since PCR-positive testd
Less than 1	7	1	14.3	0.25	0.01–1.57	0.21	0.11	0.01–0.83	0.061
1	8	0	0.0	NA	NA	NA	NA	NA	NA
2	4	0	0.0	NA	NA	NA	NA	NA	NA
3	1	0	0.0	NA	NA	NA	NA	NA	NA
4	10	0	0.0	NA	NA	NA	NA	NA	NA
5	57	23	40.4	*			*
6	168	91	54.2	1.75	0.95–3.25	0.073	2.06	1.01–4.30	0.050
7	17	9	52.9	1.66	0.57–5.05	0.360	2.67	0.74–10.2	0.139

^an = 274 participants with valid results.

^bP values were calculated using the chi-square test, results for significant associations are highlighted in bold.

^c*, reference category.

^dExcludes 2 unknowns.

^eParticipants were asked which type of patient contact describes most of their current work (excludes 5 unknowns).

^fNA, insufficient number of participants in this category.