TABLE 1.
Performance indicators for the 6 serological assays
| Assay (n) | % (95% CI) by indicator |
||||
|---|---|---|---|---|---|
| Sensitivity | Specificity | PPV | NPV | Overall agreement with PRNT results | |
| Genscript-cPass (125) | 71.07 (58.8–81.3) | 94.64 (85.1–98.8) | 94.23 (84.1–98.8) | 72.60 (60.9–82.4) | 81.6 (73.7–87.9) |
| Diasorin-S1/S2 IgG (104) | 75.47 (61.7–86.2) | 94.12 (83.8–98.8) | 93.02 (80.9–98.5) | 78.69 (66.3–88.1) | 84.61 (76.2–90.9) |
| Alinity IgG II (104) | 98.11 (89.9–99.9) | 70.59 (56.1–82.5) | 77.61 (65.8–86.9) | 97.30 (85.8–99.9) | 84.62 (76.22–90.94) |
| Diasorin-TrimericS IgG (103) | 84.91 (72.4–93.2) | 90 (78.1–96.6) | 90 (78.1–96.6) | 84.91 (72.4–93.2) | 87.37 (79.4–93.1) |
| Roche Elecsys (96) | 100 (92.6–100) | 41.67 (27.6–56.7) | 63.16 (51.3–73.9) | 100 (83.1–100) | 70.83 (60.7–79.7) |
| AESKULISA (99) | 92.31 (81.5–97.9) | 72.34 (57.4–84.4) | 78.69 (66.3–88.1) | 89.47 (75.2–97.1) | 82.82 (73.9–89.7) |