TABLE 4.
Summary of antimicrobial susceptibility profiles for 31 Flavobacterium psychrophilum isolates recovered in Chinaa
| Strains used in this study | MIC value (μg/ml) (R/M/S) of drug: |
|||||||
|---|---|---|---|---|---|---|---|---|
| AMP | ENRO | ERY | FFN | FLUQ | GEN | OXO | OXY | |
| ATCC 25922 | 2–8 | 4–16 | 4–32 | 0.06–0.25 | 0.25–1 | 0.03–0.12 | 0.12–1 | |
| ATCC 33658 | 0.06–0.25 | 0.004–0.03 | 4–16 | 0.25–1 | 0.015–0.06 | 0.25–1 | 0.008–0.03 | 0.06–0.25 |
| CN01b | <0.001 (S) | 0.0625 (R) | 0.5 (M) | 4 (R) | 2 (R) | 0.5 (M) | 0.25 (M) | 4 (M) |
| CN02b | <0.001 (S) | 0.03 (M) | 0.3 (S) | 0.5 (M) | 2 (R) | 0.5 (M) | 0.5 (R) | 4 (M) |
| CN03b | <0.001 (S) | 0.5 (R) | 0.5 (M) | 2 (R) | 1 (R) | 0.25 (M) | 0.25 (M) | 2 (M) |
| CN04b | <0.001 (S) | 0.0625 (R) | 0.5 (M) | 1 (M) | 2 (R) | 1 (M) | 0.5 (R) | 16 (R) |
| CN07b | <0.001 (S) | 0.03 (M) | 0.125 (S) | 0.5 (M) | 4 (R) | 0.5 (M) | 4 (R) | 0.0526 (M) |
| CN05c | <0.001 (S) | 1 (R) | 0.5 (M) | 1 (M) | 4 (R) | 0.5 (M) | 0.5 (R) | 8 (M) |
| CN06c | <0.001 (S) | 0.5 (R) | 0.5 (M) | 8 (R) | 4 (R) | 0.0625 (M) | 2 (R) | 4 (M) |
| CN08d | <0.001 (S) | 0.5 (R) | 8 (R) | 2 (R) | 4 (R) | 0.5 (M) | 0.5 (R) | 4 (M) |
| CN09e | 0.125 (R) | >0.5 (R) | 0.5 (M) | 0.5 (M) | 8 (R) | 0.25 (M) | 8 (R) | 0.015 (S) |
| CN10e | 0.125 (R) | >0.5 (R) | 0.5 (M) | 0.5 (M) | 8 (R) | 0.125 (M) | 8 (R) | 0.015 (S) |
| CN11e | 0.0625 (M) | 0.015 (M) | 2 (M) | 1 (M) | 0.125 (M) | 0.25 (M) | 0.125 (M) | 0.0625 (M) |
| CN12e | 0.125 (R) | 0.004 (M) | 1 (M) | 0.5 (M) | 0.0312 (M) | 0.25 (M) | 0.125 (M) | 0.015 (S) |
| CN13e | 0.125 (R) | >0.5 (R) | 0.25 (S) | 0.5 (M) | 4 (R) | 0.125 (M) | 8 (R) | <0.015 (S) |
| CN14e | 0.125 (R) | 0.5 (R) | 0.5 (M) | 0.5 (M) | 4 (R) | 0.25 (M) | 8 (R) | 0.03 (M) |
| CN15e | 0.125 (R) | 0.0625 (R) | 1 (M) | 1 (M) | 1 (R) | 0.25 (M) | 2 (R) | 0.015 (S) |
| CN16e | 0.125 (R) | 0.0625 (R) | 0.5 (M) | 0.5 (M) | 1 (R) | 0.125 (M) | 2 (R) | 0.015 (S) |
| CN17e | 0.125 (R) | 0.0625 (R) | 1 (M) | 0.5 (M) | 0.25 (R) | 0.25 (M) | 2 (R) | 0.015 (S) |
| CN18e | 0.125 (R) | 0.0625 (R) | 1 (M) | 1 (M) | 1 (R) | 0.125 (M) | 2 (R) | 0.015 (S) |
| CN19e | 0.125 (R) | 0.5 (R) | 2 (M) | 1 (M) | 16 (R) | 0.5 (M) | 16 (R) | 0.015 (S) |
| CN20e | 0.125 (R) | >0.5 (R) | 0.5 (M) | 1 (M) | 8 (R) | 0.25 (M) | 8 (R) | 0.015 (S) |
| CN21e | 0.125 (R) | >0.5 (R) | 1 (M) | 1 (M) | 8 (R) | 0.25 (M) | 8 (R) | 0.015 (S) |
| CN22e | 0.125 (R) | >0.5 (R) | 1 (M) | 1 (M) | 8 (R) | 0.25 (M) | 8 (R) | 0.015 (S) |
| CN23e | 0.125 (R) | 0.5 (R) | 2 (M) | 1 (M) | 16 (R) | 0.5 (M) | 16 (R) | 0.015 (S) |
| CN24e | 0.125 (R) | 0.125 (R) | 0.25 (S) | 0.5 (M) | 4 (R) | 0.25 (M) | 8 (R) | <0.015 (S) |
| CN25e | 0.125 (R) | >0.5 (R) | 1 (M) | 1 (M) | 4 (R) | 0.125 (M) | 8 (R) | 0.015 (S) |
| CN26e | 0.125 (R) | 0.5 (R) | 1 (M) | 1 (M) | 16 (R) | 0.25 (M) | 16 (R) | 0.015 (S) |
| CN27e | 0.125 (R) | 0.5 (R) | 1 (M) | 1 (M) | 16 (R) | 0.5 (M) | 16 (R) | 0.015 (S) |
| CN28e | 0.125 (R) | 0.5 (R) | 2 (M) | 1 (M) | 16 (R) | 0.25 (M) | 16 (R) | 0.015 (S) |
| CN29e | 0.125 (R) | 0.5 (R) | 2 (M) | 1 (M) | 16 (R) | 0.5 (M) | 16 (R) | 0.015 (S) |
| CN30e | 0.125 (R) | 0.25 (R) | 2 (M) | 1 (M) | 16 (R) | 0.25 (M) | 16 (R) | 0.015 (S) |
| CN31e | 0.125 (R) | 0.5 (R) | 2 (M) | 1 (M) | 16 (R) | 0.5 (M) | 16 (R) | 0.015 (S) |
| COWTf (μg/ml) | <0.03 to ∼0.06 | <0.002 to ∼0.03 | 0.5 to ∼4 | 0.25 to ∼1 | 0.03 to ∼0.12 | <0.06 to ∼2 | 0.06 to ∼0.25 | 0.03 to >8 |
a
R, resistant; M, moderate; S, susceptible; AMP, ampicillin; ENRO, enrofloxacin; ERY, erythromycin; FFN, florfenicol; FLUQ, flumequine; GEN, gentamicin; OXO, oxolinic acid; OXY, oxytetracycline.
b
F. psychrophilum recovered from Liaoning province.
c
F. psychrophilum recovered from Gansu province.
d
F. psychrophilum recovered from Qinghai province.
e
F. psychrophilum recovered from Heilongjiang province.
f
The epidemiological cutoff values (COWT) of F. psychrophilum to eight drugs were referenced by Van Vliet et al. (15).