Fig. 2.

The genomic landscape of BCBM using the UltraSEEK Breast Cancer Panel. The illustrated matrix presents paired BC and BM patients IDs, the genes with the identified mutations, the multiplex assays (purple indicates that 2 assays were run for these mutations) and the confidence call of the mutations. T (green): High level confidence call = high signal intensity and z-score > 10, L (red): Low level confidence call = low signal intensity and z-score 7–10. The total number of mutations, the breast–brain metastasis-free (BMFS) and the overall survival (both in months) and the receptor status are also presented. * Synchronous, NA Not available