Table 1.

UltraSEEK breast cancer panel

Genes	Missense mutations	No of mutations
AKT1	pE17K٭, pL52R٭	2
ERBB2 (HER2)	pG309A, pG309E, pS310F٭, pL755R, pL755S, pL755_T759del , pD769H٭, pD769Y, pV777L٭, pL869R٭	10
ESR1	pA283V, pK303R, pE380Q٭, pV392I, pS463P, pL536R, pL536Q, pY537C, pY537N٭, pY537S, pD538G, pS576L	12
PIK3CA	pN345K, pC420R٭, pE542K٭, pE545A, pE545K٭, pE545Q, pH1047L٭, pH1047R	8
TP53	pR175H, pR213X, pY220C, pR248Q, pR248W٭, pR273C, pR273H	7
Total	5 genes	39

The UltraSEEK BC panel screens for 39 mutations across 5 common BC oncogenes

*Multiple assays for these mutations are included in the panel