Table 1.
Correlation between menin expression and the clinico-pathological factors of 354 breast cancer patients
| Variable | Menin low (≤ 100) | Menin high (> 100) | P* | ||
|---|---|---|---|---|---|
| No. 151 |
(%) (42.7) |
No. 203 |
(%) (57.3) |
||
| Age (year) | |||||
| Mean (± SD) | 59.2 | (± 13.3) | 58.6 | (± 11.2) | 0.081† |
| Age groups | |||||
| ≤ 50 years | 31 | (20.5) | 58 | (28.6) | 0.085 |
| > 50 years | 120 | (79.5) | 145 | (71.4) | |
| BMI | |||||
| ≤ 25 | 78 | (53.4) | 133 | (67.9) | 0.007 |
| > 25 | 68 | (46.6) | 63 | (32.1) | |
| T. size | |||||
| ≤ 2 cm | 72 | (47.7) | 131 | (64.5) | |
| > 2 cm | 79 | (52.3) | 72 | (35.5) | 0.002 |
| LN invasion | |||||
| No | 64 | (42.4) | 84 | (41.1) | |
| Yes | 87 | (57.6) | 119 | (58.6) | 0.85 |
| SBR grade | |||||
| Gr 1 | 16 | (10.6) | 46 | (22.7) | 0.001 |
| Gr 2 | 68 | (45.0) | 102 | (50.2) | |
| Gr 3 | 67 | (44.4) | 55 | (27.1) | |
| ER status | |||||
| Negative | 26 | (17.2) | 20 | (9.9) | 0.041 |
| Positive | 125 | (82.8) | 183 | (90.1) | |
| PR status | |||||
| Negative | 44 | (29.1) | 44 | (21.7) | 0.108 |
| Positive | 107 | (70.9) | 159 | (78.3) | |
| Her 2 status | |||||
| Negative | 84 | (89.6) | 100 | (95.2) | 0.049 |
| Over-expressed | 12 | (10.4) | 5 | (4.8) | |
Bold indicates statistically significant values
*Correlation by Pearson’s χ2 test unless otherwise specified
†Difference between means analyzed using the Student’s t test