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. 2021 Oct 18;12:711273. doi: 10.3389/fphys.2021.711273

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Copyright © 2021 Robba, Ball, Nogas, Battaglini, Messina, Brunetti, Minetti, Castellan, Rocco and Pelosi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Intracranial pressure (ICP), partial pressure of carbon dioxide (PaCO₂), respiratory system compliance (Crs), and mean arterial pressure (MAP) at PEEP of 5 and 15 cmH₂O. Black dots and lines represent individual patient data. PEEP, positive end-expiratory pressure.