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. 2021 Nov 1;6:374. doi: 10.1038/s41392-021-00773-3

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — Kaplan–Meier curves comparing the PFS (a) and OS (b) of patients with advanced EGFR–mutant non-small-cell lung cancer who had concomitant TP53 mutations as compared to patients who had wild-type TP53. Patients who experienced ctDNA clearance at first follow-up had significantly longer survival outcomes. Kaplan–Meier curves comparing the PFS (c) and OS (d) of patients with EGFR–mutant non-small-cell lung cancer who experienced ctDNA clearance at first follow-up compared with patients who had detectable mutations