Table 1.
The demographics and Clinical parameters of CKD sub-groups.
| CKD1 (n = 33) | CKD2 (n = 26) | CKD3 (n = 25) | CKD4 (n = 16) | CKD5 (n = 19) | F/χ2 | P | |
|---|---|---|---|---|---|---|---|
| Age (years) | 43 (32,55) | 46 (29,53) | 50 (44,64) | 52 (39,62) | 53 (32,66) | 7.552 | 0.109 |
| Males (%) | 19 (58) | 18 (69) | 18 (72) | 8 (50) | 12 (63) | 2.879 | 0.523 |
| BMI (Kg/m2) | 24.3 (20.95,26.25) | 23.70 (22.80,25.10) |
24.60 (22.35,26.60) |
24.50 (21.70,27.60) |
24.20 (19.40,26.40) |
1.081 | 0.897 |
| SBP (mmHg) | 135 (130,142) | 136 (133,143) | 135 (128,150) | 143 (132,155) | 152 (135,163) | 9.881 | 0.042 |
| DBP (mmHg) | 85.03 ± 8.81 | 82.27 ± 11.63 | 81.44 ± 13.62 | 85.94 ± 14.71 | 86.53 ± 13.05 | 0.785 | 0.537 |
| eGFR (ml/min/1.73 m2) | 104.42 (94.82,115.71) |
75.20 (65.25,81.29) |
48.54 (40.50,51.61) |
22.40 (19.92,24.95) |
7.96 (6.57,11.00) | 112.4 | <0.001 |
| NGAL (ng/ml) | 209.64 (134.30,280.03) |
179.00 (156.56,206.63) |
258.00 (182.15,337.22) |
464.00 (342.30,523.82) |
506.00 (450.10,609.60) |
54.838 | <0.001 |
| CysC (mg/L) | 0.90 (0.79,1.03) | 1.11 (0.97,1.23) | 1.48 (1.32,1.71) | 2.20 (1.99,2.51) | 3.30 (3.09,3.84) | 96.911 | <0.001 |
| SCr (μmol/L) | 64 (56,78) | 95.5 (86,108.25) | 132 (123,156) | 253 (230,312.50) | 609 (459,748) | 107.216 | <0.001 |
| Alb (g/L) | 29.6 (23.15,36.80) | 35.25 (22.23,41.34) |
36.5 (33.55,41.55) | 36.50 (30.08,41.08) |
36.6 (31.30,40.40) | 8.644 | 0.071 |
| 24-h UP (g) | 2.57 (1.04,5.19) | 1.59 (0.83,4.02) | 2.00 (0.91,3.92) | 1.67 (1.15,4.41) | 4.00 (1.14,6.22) | 3.693 | 0.449 |
| Hb (g/L) | 130.52 ± 21.39 | 138.23 ± 22.89 | 127.16 ± 23.16 | 117.81 ± 23.45 | 87.26 ± 25.99 | 15.423 | <0.001 |
| Hct (L/L) | 0.38 ± 0.06 | 0.41 ± 0.06 | 0.38 ± 0.07 | 0.35 ± 0.07 | 0.26 ± 0.07 | 14.829 | <0.001 |
| Renal length (mm) | 109 (103,116) | 105 (101,110) | 97 (91.50,110) | 94 (90.25,99.75) | 89 (85,95) | 47.904 | <0.001 |
BMI, Body mass index; SBP, Systolic blood pressure; DBP, Diastolic blood pressure; Alb, albumin; 24-h UP, 24-h urinary protein; Hb, hemoglobin; Hct, hematocrit.