Table 3.
Logistic regression of risk of CVD divided by adherence rate of allopurinol and benzbromarone.
| N | No. of CVD | Crude OR (95% C.I.) | p -value | Adjusted OR†(95% C.I.) | p -value | |
|---|---|---|---|---|---|---|
| Adherence rate of allopurinol | ||||||
| None | 4,101 | 2,025 | Reference | Reference | ||
| <0.3 | 2,908 | 1,505 | 1.10 (1.00–1.21) | 0.05004 | 1.15 (1.03–1.28) | 0.017 |
| 0.3–0.6 | 266 | 125 | 0.91 (0.71–1.17) | 0.451 | 0.95 (0.73–1.23) | 0.702 |
| ≥0.7 | 137 | 51 | 0.61 (0.43–0.86) | 0.006 | 0.66 (0.46–0.96) | 0.030 |
| Adherence rate of benzbromarone | ||||||
| None | 1,450 | 698 | Reference | Reference | ||
| <0.3 | 5,072 | 2,611 | 1.14 (1.02–1.28) | 0.025 | 1.19 (1.03–1.37) | 0.015 |
| 0.3–0.6 | 647 | 306 | 0.97 (0.80–1.16) | 0.721 | 1.00 (0.82–1.23) | 0.975 |
| ≥0.7 | 243 | 91 | 0.65 (0.49–0.85) | 0.002 | 0.68 (0.50–0.91) | 0.010 |
Adjusted for allopurinol, benzbromarone, age, sex, hypertension, hyperlipidemia, chronic liver disease, diabetes, COPD, autoimmune disease, statin, and aspirin.