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. 2021 Oct 18;8:739680. doi: 10.3389/fmed.2021.739680

Table 3.

Logistic regression of risk of CVD divided by adherence rate of allopurinol and benzbromarone.

N No. of CVD Crude OR (95% C.I.) p -value Adjusted OR(95% C.I.) p -value
Adherence rate of allopurinol
   None 4,101 2,025 Reference Reference
    <0.3 2,908 1,505 1.10 (1.00–1.21) 0.05004 1.15 (1.03–1.28) 0.017
   0.3–0.6 266 125 0.91 (0.71–1.17) 0.451 0.95 (0.73–1.23) 0.702
   ≥0.7 137 51 0.61 (0.43–0.86) 0.006 0.66 (0.46–0.96) 0.030
Adherence rate of benzbromarone
   None 1,450 698 Reference Reference
    <0.3 5,072 2,611 1.14 (1.02–1.28) 0.025 1.19 (1.03–1.37) 0.015
   0.3–0.6 647 306 0.97 (0.80–1.16) 0.721 1.00 (0.82–1.23) 0.975
   ≥0.7 243 91 0.65 (0.49–0.85) 0.002 0.68 (0.50–0.91) 0.010

Adjusted for allopurinol, benzbromarone, age, sex, hypertension, hyperlipidemia, chronic liver disease, diabetes, COPD, autoimmune disease, statin, and aspirin.