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. 2021 Oct 18;12:737764. doi: 10.3389/fphar.2021.737764

FIGURE 3.

FIGURE 3

Effect of SiPE treatment on behavioural parameters in HF/STZ-induced diabetic encephalopathic rats. SiPE treatment at dose of 50, 100 or 200 mg/kg significantly improved (A) escape latency, (B) time spent in the target quadrant, (C) number of target crossing and (D) spontaneous alternation compared to DECA group. Data are presented as mean ± SD (n = 6) and one-way ANOVA test was applied. **p < 0.001 indicates statistical significance compared to NCA group. ##p < 0.001, &&p < 0.01 and $$p < 0.05 indicate statistical significance compared to DECA group.