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. 2021 Oct 18;9:724282. doi: 10.3389/fcell.2021.724282

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Copyright © 2021 Huang, Yang, Zhang, Liu, Fei, Tong, Niu and Liang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Downregulation of ALKBH5 in PDAC predicts poor prognosis. (A) Log-rank analysis of correlation between overall survival (OS) and the expression of each m⁶A regulator in tumor. (B,C) Log-rank analysis of correlation between OS or progression-free survival (PFS) and the expression of m⁶A regulators in stroma. (D–G) Kaplan–Meier analysis of correlation between OS or PFS and ALKBH5, FTO, and YTHDF1 protein expression. (H,I) Cox regression analysis for OS in PDAC patients. *P < 0.05.