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. 2021 Oct 18;12:740947. doi: 10.3389/fmicb.2021.740947

TABLE 5.

Risk factors for HPyVs baseline prevalence on the forehead of healthy individuals found in univariable logistic regression analysis.

MCPyV
HPyV6
HPyV7
TSPyV
HPyV9
HPyV10
STLPyV
Candidate variables n OR (95% CI#) p-value1 OR (95% CI#) p-value1 OR (95% CI#) p-value1 OR (95% CI#) p-value1 OR (95% CI#) p-value1 OR (95% CI#) p-value1 OR (95% CI#) p-value1
Age (per decade) 109 1.33 (0.96–1.85) 0.092 1.91 (1.35– 2.70) <0.001 1.34 (0.93– 1.93) 0.116 1.13 (0.30–4.31) 0.857 0.16 (0.01–4.95) 0.292 0.92 (0.59–1.43) 0.711 1.36 (0.86–2.17) 0.191
Sex (male vs. female) 109 2.89 (1.19–7.00) 0.019 1.12 (0.49– 2.54) 0.785 1.23 (0.41– 3.69) 0.706 0 (0) 0.998 >1 (0) 0.997 0.57 (0.17–1.98) 0.378 0.18 (0.02–1.50) 0.112
Smoking (yes vs. no) 109 1.09 (0.42–2.81) 0.867 0.76 (0.29– 2.04) 0.591 0.45 (0.09–2.13) 0.314 >1 (0) 0.997 0 (0) 0.998 0.55 (0.11–2.64) 0.451 2.04 (0.45–9.17) 0.355
Underlying disease (yes vs. no) 109 0.45 (0.01–2.36) 0.345 1.11 (0.19– 6.37) 0.907 1.27 (0.14–11.70) 0.832 0 (0) 0.999 0 (0) 0.999 1.52 (0.16–14.10) 0.714 2.74 (0.28–26.82) 0.386
Multiplicity2 (yes vs. no) 109 52.76 (6.84–406.81) <0.001 69.71 (14.91– 325.88) <0.001 27.13 (3.41–215.63) 0.002 >1 (0) 0.997 >1 (0) 0.997 21.88 (2.73–175.58) 0.004 11.13 (1.32–93.95) 0.027

OR, odds ratio; CI, confidence interval.

#Exact Clopper–Pearson confidence intervals.

1p-values < 0.05 are significant and printed in bold.

2Defined as ≥two different HPyVs at baseline.

The risk factors found for MCPyV, HPyV6, HPyV7, HPyV10, and STLPyV in univariable regression analysis were included in a multivariable logistic regression model and remained significant after adjustment for the other covariates.