TABLE 7.
Risk factors for HPyVs short-term persistence on the forehead of healthy individuals found in univariable logistic regression analysis.
| MCPyV |
HPyV6 |
HPyV7 |
HPyV10 |
STLPyV |
|||||||
| Candidate variables | n | OR (95% CI#) | p-value1 | OR (95% CI#) | p-value1 | OR (95% CI#) | p-value1 | OR (95% CI#) | p-value1 | OR (95% CI#) | p-value1 |
| Age (per decade) | 109 | 1.28 (0.94–1.73) | 0.114 | 1.88 (1.33–2.67) | <0.001 | 1.74 (1.15–2.62) | 0.009* | 0.99 (0.57–1.74) | 0.981 | 1.64 (0.98–2.74) | 0.059 |
| Sex (male vs. female) | 109 | 2.93 (1.28–6.66) | 0.011 | 0.82 (0.33–2.01) | 0.658 | 1.16 (0.33–4.06) | 0.818 | 1.03 (0.22–4.84) | 0.971 | 0.26 (0.03–2.29) | 0.223 |
| Smoking (yes vs. no) | 109 | 1.11 (0.45–2.74) | 0.821 | 0.95 (0.33–2.68) | 0.915 | 0.29 (0.04–2.40) | 0.252 | 1.30 (0.24–7.13) | 0.763 | 0 (0) | 0.998 |
| Underlying disease (yes vs. no) | 109 | 0.32 (0.06–1.81) | 0.197 | 0.62 (0.07–5.60) | 0.674 | 1.86 (0.20–17.54) | 0.588 | 3.23 (0.32–32.25) | 0.317 | 3.92 (0.38–40.19) | 0.250 |
| Multiplicity2 (yes vs. no) | 109 | 5.14 (2.13–12.41) | <0.001 | 33.27 (7.26–152.53) | <0.001 | 7.42 (1.52–36.22) | 0.013 | 9.30 (1.08–80.16) | 0.042 | 2.91 (0.51–16.59) | 0.230 |
OR, odds ratio; CI, confidence interval.
#Exact Clopper–Pearson confidence intervals.
1p-values < 0.05 are significant and printed in bold.
2Defined as ≥2 different HPyVs at baseline.
*Not significant anymore in multivariable modeling.
Short-term persistence did not occur in TSPyV and HPyV9. The risk factors found for MCPyV, HPyV6, HPyV7 and HPyV10 in univariable regression analysis were included in a multivariable logistic regression model and remained significant after adjustment for the other covariates, with the exception of age for HPyV7.