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. 2021 Oct 18;12:747106. doi: 10.3389/fphys.2021.747106

TABLE 5.

Regression models for association between % blood pressure dipping and obstructive sleep apnea severity measures.

%SBP dip
%DBP dip
%MAP dip
Unadjusted β (95% CI) Adjusted* β (95% CI) Unadjusted β (95% CI) Adjusted* β (95% CI) Unadjusted β (95% CI) Adjusted* β (95% CI)
AHI −0.05 (−0.10, 0.01) 0.11 (0.20,0.02) 0.11 (0.19,0.03) 0.16 (0.29,0.04) 0.08 (0.15,0.01) 0.13 (0.24,0.02)
REM-AHI −0.00 (−0.10, 0.10) −0.03 (−0.10, 0.10) −0.06 (−0.15, 0.03) −0.05 (−0.17, 0.07) −0.05 (−0.12, 0.03) −0.05 (−0.15, 0.05)
NREM-AHI −0.03 (−0.10, 0.03) −0.08 (−0.20, 0.02) −0.09 (−0.17, −0.01) −0.13 (−0.26, 0.01) −0.07 (−0.14, 0.01) −0.11 (−0.22, 0.01)
4% ODI 0.08 (0.15,0.02) 0.15 (0.23,0.06) 0.17 (0.26,0.09) 0.23 (0.35,0.11) 0.13 (0.21,0.06) 0.18 (0.30,0.09)
Resp arousal index −0.03 (−0.11, 0.05) −0.06 (−0.18, 0.05) −0.09 (−0.21, 0.03) −0.08 (−0.25, 0.09) −0.06 (−0.16, 0.04) −0.06 (−0.21, 0.09)
Nadir SpO2 0.08 (−0.15, 0.31) 0.11 (−0.21, 0.43) 0.44 (0.13, 0.76) 0.56 (0.13, 0.99) 0.30 (0.03, 0.58) 0.38 (0.00, 0.76)
TST < 90% 0.19 (0.37, 0.00) 0.32 (0.57,0.07) 0.50 (0.74,0.26) 0.67 (0.99,0.34) 0.37 (0.58,0.16) 0.54 (0.82,0.26)
Microarousal index −0.02 (−0.10, 0.05) −0.05 (−0.17, 0.08) −0.09 (−0.20, 0.02) −0.09 (−0.27, 0.08) −0.06 (−0.16, 0.04) −0.06 (−0.22, 0.09)
Total sleep time 0.05 (−0.90, 0.99) 0.00 (−1.04, 1.05) 0.05 (−1.36, 1.46) −0.01 (−1.51, 1.49) −0.28 (−1.46, 0.90) −0.40 (−1.66, 0.87)

*Adjusted with age, body mass index at enrolment, parity, number of BP medications, gestational age at blood pressure assessment.

% Blood pressure dip = 100 × (daytime-nighttime blood pressure)/daytime blood pressure. SBP, systolic blood pressure; DBP, diastolic blood pressure; MAP, mean arterial pressure, AHI, apnea-hypopnea index; REM-AHI, apnea-hypopnea index during REM sleep; NREM-AHI, apnea-hypopnea index during NREM sleep; 4% ODI, 4% oxygen desaturation index; Resp arousal index, respiratory arousal index; SpO2, oxygen saturation during sleep; TST < 90%, total sleep time with oxygen saturation < 90%.

Bold values means p-value < 0.05.