Table 1.
CMV role in lymphoma development.
| Study | Aim of study | Results |
|---|---|---|
| Gupta et al. (38) | Seroprevalence SS/MF vs Non-SS/MF |
SS/MF 60.4 % (N=53) Non-SS/MF 61.5% (N=26) |
| Ballanger et al. (39) | Seroprevalence SS, MF& control group | Control group 37% (N=124) MF 66.67% (N=27) SS 42.86% (N=21) p=0.009 |
| PCR in affected tissue | CMV was not detected in diagnostic biopsies. CMV was detected in two SS skin biopsies realized at an advanced stage | |
| Herne et al. (40) | Seroprevalence SS/MF vs bone marrow donors | Control group 57.3% (N=1322) MF/SS 97.4% (N=116) p<0.05 |
| Subanalysis with age-matched subgroups | CTCL 93% (N=32) Control group 53.6% (N=1103) p<0.05 |
|
| Mehravaran et al. (41) | PCR in affected tissue IE1 (active replication) | IE1 detected in 1/25 Non-HL |
| Nested-PCR in affected tissue UL138 (latency) Hodgkin and No Hodgkin |
UL138 in 5/25 Non-HL and 1/25 HL |
SS, Sézary Syndrome; MF, Mycosis Fungoides; CTCL, Cutaneous T-cell lymphoma; HL, Hodgkin lymphoma.