TABLE 2.
Particle size and zeta potential of free micelles and bedaquiline-loading micelles based on DLS.
| Free micelles | Bedaquiline-loading micelles | ||
| pH 7.4 | Size | 322.4 ± 2.69 | 260.2 ± 2.02 |
| PDI | 0.146 ± 0.03 | 0.145 ± 0.02 | |
| ζ | 39.8 ± 0.45 | 47.1 ± 0.74 | |
| pH 6 | Size | 905.8 ± 35.73 | 1133.0 ± 40.43 |
| PDI | 0.248 ± 0.03 | 0.071 ± 0.01 | |
| ζ | 4.97 ± 1.03 | –0.09 ± 0.15 | |
| pH 5 | Size | – | – |
| PDI | – | – | |
| ζ | 47.8 ± 2.84 | –0.36 ± 0.57 |
mPEG-b-PDPA, methoxypolyethylene glycol-b-poly-2-(diisopropylamino)ethyl methacrylate; GPC, gel permeation chromatography; PDI, polydispersity index; CMC, critical micelles concentrations; DLS, dynamic light scattering.