Table 4.
Cox regression analysis of miR-182-5p expression as a tumor recurrence predictor
| Variables | Univariate Cox's regression analysis | Multivariate Cox's regression analysis | ||
|---|---|---|---|---|
| RR (95%CI) | p-value | RR (95%CI) | p-value | |
| Age (years) | ||||
| <65 versus >65 | 1.203 (0.891-1.6223) | 0.227 | NA | NA |
| Gender | ||||
| Male versus Female | 0.953 (0.713-1.275) | 0.746 | NA | NA |
| Pathological stage | ||||
| I/IIIa versus IIIb+IV | 1.385 (0.771-2.488) | 0.276 | NA | NA |
| T stage | ||||
| T1+T2 versus T3+T4 | 1.956 (1.305-2.931) | 0.001 | 1.881 (1.254-2.823) | 0.002 |
| N stage | ||||
| Negative versus Positive | 1.484 (1.103-1.995) | 0.009 | NA | NA |
| M stage | ||||
| Negative versus Positive | 1.114 (0.812-1.528) | 0.503 | NA | NA |
| miR-182-5p expression | ||||
| High versus Low | 0.711 (0.514-0.985) | 0.040 | 0.691 (0.498-0.960) | 0.028 |
RR: risk ratio; CI: confidence interval; NA: not analyzed.