Table 5.
Cox regression analysis of prognostic factors for overall survival of lung adenocarcinoma
| Variables | Univariate Cox's regression analysis | Multivariate Cox's regression analysis | ||
|---|---|---|---|---|
| RR (95%CI) | p-value | RR (95%CI) | p-value | |
| Age (years) | ||||
| <65 versus >65 | 0.853 (0.633-1.148) | 0.293 | NA | NA |
| Gender | ||||
| Male versus Female | 0.942 (0.704-1.260) | 0.688 | NA | NA |
| Pathological stage | ||||
| I/ IIIa versus IIIb+IV | 2.171 (1.401-3.364) | 0.001 | NA | NA |
| T stage | ||||
| T1+T2 versus T3+T4 | 2.411 (1.666-3.487) | 0.000 | 2.170 (1.493-3.154) | <0.001 |
| N stage | ||||
| Negative versus Positive | 2.550 (1.903-3.417) | 0.000 | 2.298 (1.709-3.091) | <0.001 |
| M stage | ||||
| Negative versus Positive | 0.952 (0.847-1.070) | 0.409 | NA | NA |
| EPAS1 expression | ||||
| High versus Low | 1.407 (1.038-1.906) | 0.028 | 1.478 (1.087-2.008) | 0.013 |
RR: risk ratio; CI: confidence interval; NA: not analyzed.