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. 2021 Oct 21;12(23):7158–7166. doi: 10.7150/jca.61567

Figure 2.

Figure 2

GOLM1 promotes CRC invasion and metastasis in vivo and in vitro. (A) GOLM1 expression in SW480 and SW620 cells by Western blot. (B) Transwell assays indicated that upregulation of GOLM1 promotes CRC migration and invasion, and depletion of GOLM1 inhibits the migration and invasion potentials of CRC cells. (C-H) Metastasis assays in the immune-competent C57BL/6 mice. Bioluminescent imaging(C), Bioluminescent signals(D), Overall survival(E), The incidence and number of lung and liver colonization(F-G), and HE (H). * P<0.05.