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EZH2 could epigenetically repress PCAT18 expression by H3K27me3 modification. A. The expression of EZH2 in TCGA data of GC. B. Western blot analysis and qPCR of the expression levels of EZH2after cell treatment with si-EZH2 both in SGC7901as well as AGS cells. C. The expression of PCAT18 following EZH2's knockdown. D. ChIP-qPCR of H3K27me3 and EZH2 of the promoter region of the PCAT18 locus following siRNA treatment aimed at si-EZH2 or si-NC in SGC7901 cells. *P < 0.05, **P < 0.01.
