Silencing CKS2 expression by treatment with an anti-CKS2 siRNA attenuates LUAD cell proliferation. (A) Relative CKS2 mRNA expression levels in A549 and H1299 LUAD cells transfected with si-1, si-2, si-3 siRNAs against CKS2 and NC siRNA, as determined by qRT-PCR. (B) Relative CKS2 protein expression levels in A549 and H1299 cells transfected with si-1, si-2, si-3 siRNAs against CKS2 and NC siRNA, as revealed by western blotting. (C, D) Decreased survival of A549 and H1299 cells transfected with si-1 siRNA against CKS2, as shown by the CCK-8 assay (*P < 0.05, **P < 0.01, ***P < 0.001 vs. cells treated by NC siRNA).