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. 2021 Oct 17;12(23):7088–7100. doi: 10.7150/jca.62526

Figure 6.

Figure 6

miR-92b-3p regulates XIST and NLK expressions via directly binding to their mRNAs. (A) The wild type and mutated miR-92b-3p binding sites in the XIST 3'-UTR are shown in the upper panel. miR-92b-3p mimic and luciferase constructs were co-transfected into 293T cells. Luciferase activity of wild type and mutant Luc XIST are shown in the lower panel. (B)The wild type and mutated miR-92b-3p binding sites in the NLK 3'-UTR are shown in the upper panel. Luciferase activity of wild type and mutant Luc NLK are shown in the lower panel. P <0.05 vs. control group.