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. 2021 Oct 28;18(10):825–835. doi: 10.11909/j.issn.1671-5411.2021.10.004

Table 1. Characteristics of study population.

Characteristics Without HAVB (n = 152) HAVB (n = 29) P-value
Data are presented as means ± SD or n (%). &Presented as median (interquartile range). *Presented as the differential between patients with L-R fusion and other subtypes of type-1 morphology. **Presented as the differential between patients with calcified raphe and non-calcified raphe. AAo: ascending aorta; HAVB: high-degree atrioventricular block; L-R: left- and right-coronary cusps; NYHA: New York Heart Association; STS: Society of Thoracic Surgeons; TAVI: transcatheter aortic valve implantation.
Female 68 (44.7%) 10 (34.5%) 0.307
Age, yrs 72.8 ± 6.1 74.1 ± 6.8 0.339
Body mass index, kg/m2 22.6 ± 3.8 22.6 ± 2.9 0.969
STS score, % 6.1 ± 4.3 7.4 ± 4.0 0.115
NYHA class > 2 133 (87.5%) 25 (86.2%) 0.768
Hypertension 58 (38.2%) 12 (41.4%) 0.744
Diabetes mellitus 30 (19.7%) 5 (17.2%) 0.755
Chronic obstructive pulmonary disease 68 (44.7%) 16 (55.2%) 0.302
Coronary artery disease 54 (35.5%) 13 (44.8%) 0.342
Peripheral vessel disease 59 (38.8%) 13 (44.8%) 0.544
Cerebrovascular disease 29 (19.1%) 6 (20.7%) 0.840
Creatinine, umol/L 83.0 (70.0−100.0)& 91.0 (76.0−115.0)& 0.143
Echocardiographic parameters
 Peak jet velocity, m/s 5.1 ± 0.8 5.0 ± 0.8 0.366
 Mean pressure gradient, mmHg 65.3 ± 21.5 62.3 ± 19.4 0.544
 Baseline ejection fraction, % 54.8 ± 15.8 55.2 ± 14.6 0.883
 Baseline aortic regurgitation > mild 28 (18.4%) 8 (27.6%) 0.257
 Baseline mitral regurgitation > mild 26 (17.1%) 7 (24.1%) 0.369
Anatomic parameters
 AAo perimeter, mm 112.3 ± 13.2 112.0 ± 11.6 0.915
 AAo angle, ° 18.6 (13.8−22.6)& 24.2 (16.9−29.5)& 0.002
 Sinotubular junction perimeter, mm 96.3 ± 13.3 98.0 ± 11.6 0.481
 Annular perimeter, mm 77.6 ± 9.0 78.6 ± 8.5 0.569
 Membranous septum length, mm 4.2 ± 2.1 3.8 ± 2.1 0.374
 Type-1 morphology 57 (37.5%) 22 (75.9%) < 0.001
  L-R fusion 43 (75.4%) 20 (90.9%) 0.211*
  Calcified raphe 32 (56.1%) 10 (45.4%) 0.394**
 HU-850 valve calcium volume, mm3 698.3 (355.3−1017.5)& 388.2 (244.7−742.7)& 0.019
  Excess leaflet calcification 75 (49.3%) 9 (31.0%) 0.070
 HU-850 left ventricular outflow track calcium volume, mm3 0 (0.0−33.3)& 0 (0.0−10.0)& 0.188
  Membranous septum calcification 16 (10.5%) 1 (3.4%) 0.316
  Aortomitral curtain calcification ≥ moderate 19 (12.5%) 6 (20.7%) 0.246
Preoperative electrocardiography
 Atrial fibrillation 20 (13.2%) 4 (13.8%) 0.926
 1° atrioventricular block 4 (2.6%) 1 (3.4%) 0.806
 Right bundle branch block 6 (3.9%) 3 (10.3%) 0.146
 Left bundle branch block 5 (3.3%) 0 0.710
Procedural and post-procedural characters
 Pre-TAVI dilation 151 (99.3%) 28 (96.6%) 0.296
 Post-TAVI dilation 92 (60.5%) 17 (59.6%) 0.848
 Device 0.392
  VenusA/VenusA-plus 129 (84.9%) 23 (79.3%)
  Corevalve 8 (5.3%) 1 (3.4%)
  VitaFlow 10 (6.6%) 2 (6.9%)
  TaurasOne 5 (3.3%) 3 (10.3%)
Oversizing ratio, % 6.5 ± 9.4 6.6 ± 9.0 0.928
Implantation depth > membranous septum length 96 (63.2%) 26 (89.7%) 0.005