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. 2021 Oct 28;18(10):816–824. doi: 10.11909/j.issn.1671-5411.2021.10.001

Table 2. Adjusted hazard ratio of cardiovascular mortality for first-degree familial histories of different cardiovascular diseases. Estimates were adjusted for age, sex, systolic blood pressure, diastolic blood pressure, body mass index, smoking, fasting glucose, low-density lipoprotein cholesterol and triglycerides.

Variables Cardiovascular mortality
Adjusted hazard ratio (95% CI) P-value
*Refers to the P < 0.05. CHD: coronary heart disease.
Paternal history of disease
 Hypertension 1.18 (0.93−1.49) 0.167
 Diabetes mellitus 0.89 (0.61−1.30) 0.548
 Hyperlipidemia 0.98 (0.52−1.84) 0.944
 CHD 1.29 (1.07−1.55) 0.009*
 CHD before 60 yrs 1.40 (1.08−1.82) 0.011*
 Stroke 1.11 (0.90−1.37) 0.338
 Peripheral arterial disease 1.05 (0.81−1.37) 0.708
Maternal history of disease
 Hypertension 1.00 (0.83−1.21) 0.981
 Diabetes mellitus 1.32 (1.02−1.70) 0.032*
 Hyperlipidemia 1.07 (0.62−1.87) 0.803
 CHD 1.27 (1.03−1.56) 0.027*
 CHD before 60 yrs 1.71 (1.25−2.35) 0.001*
 Stroke 0.99 (0.80−1.23) 0.944
 Peripheral arterial disease 1.20 (0.92−1.57) 0.181
Sibling history of disease
 Hypertension 1.43 (1.16−1.77) 0.001*
 Diabetes mellitus 1.22 (0.94−1.58) 0.131
 Hyperlipidemia 1.58 (1.11−2.25) 0.010*
 CHD Not available Not available
 CHD before 60 yrs 1.34 (1.09−1.64) 0.006*
 Stroke 1.09 (0.79−1.49) 0.605
 Peripheral arterial disease 1.05 (0.73−1.49) 0.803