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. 2021 Oct 28;20:15330338211045831. doi: 10.1177/15330338211045831

Figure 3.

Figure 3.

Knockdown of CBX2 repressed tumor growth in vivo. (A) Fluc bioluminescence images showing the tumors in the nude mouse xenograft model. (B) Overall survival analysis demonstrated that CBX2 downregulation improved the survival time (P < .05). (C) The mouse body weights were evaluated. (D) Images of HE-stained tumor tissue. (E) The expression of CBX2 and Ki67 was analyzed by IHC staining. (F and G) The expression of EMT markers, E-cadherin, N-cadherin, slug, and slug were detected with IHC.

Abbreviations: CBX, ChromoBox; HE, hematoxylin and eosin; EMT, epithelial to mesenchymal transition; IHC, immunohistochemistry.