Table 9.

Brain regions with significant increase in activation in the mediation analysis for the processing of information conveyed by event (surprise) in UVT-A

Regions	L/R	BA	x	y	z	Z	K
Path a
Superior temporal gyrus a	L	41/42	−58	−24	14	0.46	26770
Mid temporal gyrus	R	21	58	−40	8	0.41
Ventral striatum	L/R		0	−4	−2	0.34
Anterior cingulate cortex	L	32	−2	6	44	0.33
Anterior insular cortex	L		−36	14	4	0.30
Superior temporal gyrus a	R	41/42	53	−36	15	0.27
Inferior parietal lobule b	L	7/40	−48	−30	44	0.26
Thalamus	L		−10	−15	9	0.23
Superior temporal gyrus	R	22	56	−12	0	0.23
Inferior parietal lobule b	R	7/40	40	−42	60	0.20
Caudate nucleus	R		6	3	2	0.20
Caudate nucleus	L		−11	6	2	0.19
Inferior parietal lobule	R	7/40	45	−35	51	0.19
Thalamus	R		14	−13	9	0.18
Superior frontal gyrus c	R	6/8	28	−14	70	0.18
Precentral gyrus	L	6	−54	4	32	0.17
Superior frontal gyrus c	L	6/8	−27	−10	57	0.15
Inferior frontal gyrus	R	44	52	12	28	0.13
Hippocampus	R	35	26	−12	−8	0.12
Inferior frontal gyrus	R	45	44	34	18	0.10
Calcarine cortex	R	17	6	−80	10	0.23	81
Posterior cingulate cortex	R	23	2	−24	30	0.22	145
Cerebellum IX	L		−8	−44	−40	0.16	334
Cerebellum IV & V	L		−16	−54	−18	0.14
Precuneus	R	7	10	−50	42	0.15	90
Cerebellum VI	R		20	−54	−20	0.15	607
Vermis VIII			6	−66	−36	0.10	95
Path b
Superior frontal gyrus c	L	6/8	−28	−6	50	5.19	35599
Superior frontal gyrus c	R	6/8	20	−6	60	4.79
Inferior parietal lobule	L	7/40	−30	−34	42	4.66
Anterior cingulate cortex	L	32	−10	12	46	4.59
Inferior parietal lobule	R	7/40	20	−36	60	4.11
Mid occipital gyrus	L	19	−26	−64	30	4.05
Precentral gyrus	L	6	−36	2	28	3.93
Supplementary motor area	L	6	−10	−20	58	3.67
Postcentral gyrus	R	2/3	36	−28	42	3.66
Calcarine cortex	R	17	24	−68	20	3.49
Postcentral gyrus	L	3	−50	−20	32	3.42
Anterior cingulate cortex	R	24/32	10	12	32	3.30
Mid temporal gyrus	R	22	42	−52	14	3.23
Precuneus	L	7	−10	−56	56	3.23
Inferior temporal gyrus	L	20	−46	−48	−10	3.21
Postcentral gyrus	R	2/3	62	−12	24	3.20
Inferior temporal gyrus	R	20	48	−44	−14	3.05
Thalamus	L		−18	−24	0	2.89
Mid frontal gyrus	L	46	−28	42	14	2.69
Lingual gyrus	R	18	22	−54	−2	2.62
Mid occipital gyrus	R	19	46	−80	2	2.50
Calcarine cortex	L	17	−14	−90	14	2.46
Lingual gyrus	L	18	−16	−62	0	2.27
Cerebellum IV & V	R		34	−30	−28	2.17
Cerebellum VI	R		28	−62	−26	2.02
Superior parietal lobule	L	7	−14	−80	48	1.90
Anterior insular cortex	L		−28	24	−2	3.39	861
Anterior insular cortex	R		30	24	4	2.80	1080
Posterior insular cortex	R		36	−4	8	2.78
Posterior insular cortex	L		−34	−14	2	2.11	61
Mediation
Supplementary motor aread	L	6/32	−6	10	46	0.62	723
Postcentral gyrus	L	2/3	−56	−18	28	0.60	1830
Inferior parietal lobule	L	7/40	−34	−34	44	0.57
Superior temporal gyrus	L	22	−48	−32	8	0.35
Posterior insular cortex	L		−50	−6	4	0.25
Supramarginal gyrus	R	40	58	−16	24	0.54	783
Superior temporal gyrus	R	42	58	−40	14	0.37
Superior frontal gyrus c	L	6/8	−30	−8	52	0.41	149
Paracentral lobule	L	4	−18	−12	68	0.39	156
Postcentral gyrus	R	2/3	46	−30	50	0.39	242
Anterior insular cortex	L		−30	20	6	0.35	141
Anterior insular cortex	R		52	6	−8	0.33	389
Superior frontal gyrus c	R	6/8	22	−6	58	0.33	158
Mid temporal gyrus	R	21	58	−52	18	0.33	161
Calcarine cortex	L	17	−12	−68	14	0.32	219
Inferior frontal gyrus	L	44	−54	12	0	0.29	116

Note:

^aExtending to posterior insular cortex.

^bExtending to postcentral gyrus.

^cComposing the FEF.

^dExtending to the ACC.