Table 3.
Survival Analysis of Different Risk Groups and Combination Analysis
| Variables | OS | OS* | ||
|---|---|---|---|---|
| Crude HR (95% CI) | Crude P | Adjusted HR (95% CI) | Adjusted P | |
| Low-risk group | 1 | 1 | ||
| High-risk group | 1.529 (1.242–1.882) | <0.001 | 1.400 (1.078–1.819) | 0.012 |
| High ALI and low-risk group | 1 | 1 | ||
| High ALI and High-risk group | 2.238 (1.743–2.874) | <0.001 | 2.260 (1.666–3.065) | <0.001 |
| Low ALI and Low-risk group | 1.524 (1.035–2.245) | 0.033 | 1.685 (1.105–2.570) | 0.015 |
| Low ALI and High-risk group | 2.973 (2.242–3.943) | <0.001 | 3.095 (2.085–4.592) | <0.001 |
Notes: *Adjusted for age, sex and TNM stage; adjusted for age, sex, TNM stage, radical resection, postoperative chemoradiotherapy, ECOG PS, KPS, BMI, family history of cancer, tea consumption, alcohol consumption, smoking, diabetes, hypertension, coronary heart disease, AST, ALT, hemoglobin, serum total protein, serum albumin, WBC, lymphocytes, neutrophils, platelet, 30-day mortality, PGSGA, nutritional intervention.
Abbreviations: OS, overall survival; HR, hazards ratio; CI, confidence interval; BMI, body mass index; ECOG PS, Eastern Cooperative Oncology Group Performance Status; KPS, Karnofsky Performance Status; AST, aspartate aminotransferase; ALT, alanine transaminase; WBC, white blood cells; ALI, advanced lung cancer inflammation index; NLR, neutrophil–lymphocyte ratio; PNI, prognostic nutritional index; SII, systemic immune-inflammation index; PLR, platelet–lymphocyte ratio; PGSGA, Patient-Generated Subjective Global Assessment.