Table 1. Data collection and refinement statistics.

	hHVEM–hLIGHT	hHVEM–hLIGHT–hCD160	mHVEM
Data collection
Wavelength used (Å)	1.075	0.97931	0.97931
Resolution range (Å)	2.30-50.00 (2.30-2.34)	3.50-50.00 (3.50-3.83)	2.10-50.00 (2.10-2.14)
Space group	P212121	I23	P41212
Unit cell (Å)	a = 111.7, b = 113.6, c = 163.3	a = b = c = 214.7	a = b = 64.7, c = 69.0
Unique reflections (N)	92,792	20,868	8,989
Redundancy	10.8(10.7)	20.7 (17.9)	13.5 (9.9)
Completeness	99.9(99.7)	99.9 (100)	99.5 (99.1)
I/sigma	22.7 (3.1)	16.1 (2.2)	17.1 (2.2)
Rmergea	0.125 (0.936)	0.191 (1.674)	0.135 (0.938)
CC1/2	N/A	0.999 (0.676)	0.999 (0.943)
Refinement
Resolution range (Å)	2.30-48.92 (2.30-2.36)	3.50-19.93 (3.50-3.59)	2.10-20.00 (2.10-2.16)
Rworkb	0.188 (0.245)	0.257 (0.370)	0.212 (0.355)
Rfree	0.231 (0.270)	0.285 (0.293)	0.257 (0.328)
Average B factor (Å2)	38.4	139.9	55.5
Rms bond (Å)	0.021	0.005	0.018
Rms angles (°)	2.081	1.290	1.928
PDB code	4RSU	7MSG	7MSJ

Parentheses indicate statistics for the highest-resolution bin. Rms, root mean square. N, numbers.

^aR_merge = Σ_hklΣ_i|I_i(hkl) − <I(hkl)>|/Σ_hklΣ_iI_i(hkl).

^bR_work = Σ|F_c − F_o|/ΣF_o.