Table 1.
Whole cohort (n = 117) | Hyponatremic (group A, n = 31) | Normonatremic (group B, n = 78) | Hypernatremic (group C, n = 8) | P value | |
---|---|---|---|---|---|
Age (years) | 64 ± 13 (25–90) | 61 ± 12 (25–83) | 63 ± 13(36–90) | 71 ± 11 (53–88) | 0.190 |
Gender (Male) | 81 (69) | 23 (28) | 51 (63) | 7 (9) | 0.341 |
ICU admission | 18 (15) | 7 (39) | 10 (56) | 1 (5) | 0.432 |
Need for mechanical ventilation in ICU | 32 (27) | 10 (31) | 21 (66) | 1 (3) | 0.530 |
Length of hospital stay (days) | 33 ± 22 (4–120) | 29 ± 17 (7–82) | 27 ± 22 (4–120) | 27 ± 18 (11–66) | 0.391 |
Death | 20 (17) | 4 (20) | 15 (75) | 1 (5) | 0.686 |
IL-6, maximum (pg/mL) | 404.9 ± 776.7 (7.4–4601.0) | 325.1 ± 450.6 (9.8–2140.0) | 342.7 ± 623.5 (3.5–3207.0) | 1001.2 ± 1784.8 (61.1–4601.0) | 0.385 |
CRP, admission (mg/dL) | 8.6 ± 8.0 (0.6–41.5) | 10.5 ± 10.0 (1.0–41.5) | 7.0 ± 5.7 (0.3–27.3) | 3.5 ± 2.4 (0.3–6.2) | 0.029 (A vs C) |
Lac, admission (mmol/mol) | 0.9 ± 0.8 (0.0–3.6) | 1.0 ± 0.7 (0.0–2.5) | 0.7 ± 0.8 (0.0–3.6) | 0.8 ± 0.8 (0.0–2.0) | 0.107 |
CRP, C reactive protein; ICU, intensive care unit; IL-6, interleukin 6; Lac, serum lactate levels.
Bold indicates statistical significance, P = 0.029.