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. 2021 Oct 20;14:5403–5417. doi: 10.2147/JIR.S331010

Table 3.

Association Between Predictor Variables and Colorectal Cancer (CRC) Determined via Bivariate and Multivariate Logistics Regression Analysis

Variables CRCs Adenomas Bivariate OR (95% CI) p value Multivariate OR (95% CI) p value
Age (Y) ≤65 23 55 0.28 (0.13,0.6) 0.001 0.14 (0.05,0.44) 0.001
>65 27 18 Ref Ref
Location Right side 5 18 0.34 (0.12,0.99) 0.047 0.54 (0.13,2.27) 0.396
Left side 45 55 Ref Ref
Sex Male 30 55 0.88 (0.42,1.84) 0.736
Female 20 18 Ref
PD-1 High 24 12 4.69 (2.04,10.77) <0.001 1.46 (0.45,4.77) 0.530
Low 26 61 Ref Ref
PD-L1 High 21 14 3.05 (1.36,6.85) 0.007 1.61 (0.49,5.23) 0.431
Low 29 59 Ref Ref
XRCC1 High 28 15 4.92 (2.22,10.91) <0.001 3.84 (1.37,10.78) 0.011
Low 22 58 Ref Ref
FOXP3 High 35 15 9.02 (3.94,20.68) <0.001 11.66 (3.74,36.35) <0.001
Low 15 58 Ref Ref
CD4 High 34 31 2.88 (1.35,6.12) 0.006 1.68 (0.56,5.09) 0.357
Low 16 42 Ref Ref
XRCC1 rs25487 Wild 33 32 2.49 (1.18,5.24) 0.017 3.38 (1.15,9.95) 0.027
Mutant 17 41 Ref Ref

Notes: Bold values, the statistically significant (P-value < 0.05).

Abbreviation: OR, adjusted odds ratio.