Table 3.
Variables | CRCs | Adenomas | Bivariate OR (95% CI) | p value | Multivariate OR (95% CI) | p value | |
---|---|---|---|---|---|---|---|
Age (Y) | ≤65 | 23 | 55 | 0.28 (0.13,0.6) | 0.001 | 0.14 (0.05,0.44) | 0.001 |
>65 | 27 | 18 | Ref | Ref | |||
Location | Right side | 5 | 18 | 0.34 (0.12,0.99) | 0.047 | 0.54 (0.13,2.27) | 0.396 |
Left side | 45 | 55 | Ref | Ref | |||
Sex | Male | 30 | 55 | 0.88 (0.42,1.84) | 0.736 | – | – |
Female | 20 | 18 | Ref | ||||
PD-1 | High | 24 | 12 | 4.69 (2.04,10.77) | <0.001 | 1.46 (0.45,4.77) | 0.530 |
Low | 26 | 61 | Ref | Ref | |||
PD-L1 | High | 21 | 14 | 3.05 (1.36,6.85) | 0.007 | 1.61 (0.49,5.23) | 0.431 |
Low | 29 | 59 | Ref | Ref | |||
XRCC1 | High | 28 | 15 | 4.92 (2.22,10.91) | <0.001 | 3.84 (1.37,10.78) | 0.011 |
Low | 22 | 58 | Ref | Ref | |||
FOXP3 | High | 35 | 15 | 9.02 (3.94,20.68) | <0.001 | 11.66 (3.74,36.35) | <0.001 |
Low | 15 | 58 | Ref | Ref | |||
CD4 | High | 34 | 31 | 2.88 (1.35,6.12) | 0.006 | 1.68 (0.56,5.09) | 0.357 |
Low | 16 | 42 | Ref | Ref | |||
XRCC1 rs25487 | Wild | 33 | 32 | 2.49 (1.18,5.24) | 0.017 | 3.38 (1.15,9.95) | 0.027 |
Mutant | 17 | 41 | Ref | Ref |
Notes: Bold values, the statistically significant (P-value < 0.05).
Abbreviation: OR, adjusted odds ratio.